Before she became a YouTube star, Dr. Sandra Lee was — and still is — practicing dermatology in Upland, California, according to a July 2019 Refinery 29 report. As of June 2021, dermatologists in the area reportedly bring in an average of $377,900 yearly, per Salary.com. Everything changed when Lee started posting extraction videos on her YouTube channel in 2015. 

"Before YouTube demonetized, posting my videos was quite lucrative. At one point, my channel was bringing in six figures a month, and that was ridiculous," she told WealthSimple in August 2018. She then landed her popular TLC show in 2018, "Dr. Pimple Popper." "I'm not getting paid anything for the show, really. But I'm so fortunate to have this — that this has been offered to me," she told the outlet. She also earns money from sponsored Instagram posts, which can net her approximately $13,219 per post, via Compare The Market. All said and done, Lee is worth an estimated $5 million, according to Celebrity Net Worth.

In addition to her robust online presence, she also sells her own skincare line, SLMD. However, when it comes to managing money, she leaves that to her husband. "I'm still not really good with money. I'm not breaking the bank, but that's mostly because of my husband, Jeff. He really holds things down," she told WealthSimple.

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